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Modern Day Analysis of AEDs

Modern Day Analysis of AEDs

Sun Sep 22 3:30 PM - 4:10 PM

  • Imperial D

This will include the various analytical methodologies (e.g. LC/MS, immunoassays particularly for new AEDs, etc.); the need to participate in QA schemes and to “recommend” as to what should be expected from a modern AED TDM Laboratory service.


Objectives:

At the end of this session the participants will be able to:

  • Discuss the benefits and limitations of immunoassays for AED TDM
  • Discuss the benefits and limitations of LC-MS methods for AED TDM
  • Describe technology developments in high resolution mass spectrometry and alternative calibration strategies in LC-MS and their potential impact on AED TDM
  • Recognize the importance of robust EQA programs in harmonization of AED TDM methods.

Description:

This session will discuss various analytical approaches to measurement of AEDs in blood and other matrices. Particular focus will be given to LC-MS and immunoassay methodologies. Additional focus will center around the need for clinical laboratory method harmonization and participation in external QA and proficiency testing schemes.

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Pre-Congress Symposium: 100 Years of Antiepileptic Drugs: The Role of TDM in Optimizing Patient Care